BDBM50300453 2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyacetamide::CHEMBL583967

SMILES: ONC(=O)C(c1ccc2OCCc2c1)c1ccc2OCCc2c1

InChI Key: InChIKey=WEOWFSNVPPFUOU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 5 (Homo sapiens (Human))	BDBM50300453 (2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...) Show SMILES ONC(=O)C(c1ccc2OCCc2c1)c1ccc2OCCc2c1 Show InChI InChI=1S/C18H17NO4/c20-18(19-21)17(13-1-3-15-11(9-13)5-7-22-15)14-2-4-16-12(10-14)6-8-23-16/h1-4,9-10,17,21H,5-8H2,(H,19,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50300453 (2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...) Show SMILES ONC(=O)C(c1ccc2OCCc2c1)c1ccc2OCCc2c1 Show InChI InChI=1S/C18H17NO4/c20-18(19-21)17(13-1-3-15-11(9-13)5-7-22-15)14-2-4-16-12(10-14)6-8-23-16/h1-4,9-10,17,21H,5-8H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50300453 (2,2-bis(2,3-dihydrobenzofuran-5-yl)-N-hydroxyaceta...) Show SMILES ONC(=O)C(c1ccc2OCCc2c1)c1ccc2OCCc2c1 Show InChI InChI=1S/C18H17NO4/c20-18(19-21)17(13-1-3-15-11(9-13)5-7-22-15)14-2-4-16-12(10-14)6-8-23-16/h1-4,9-10,17,21H,5-8H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysis				Bioorg Med Chem Lett 19: 5684-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.010 BindingDB Entry DOI: 10.7270/Q2NZ87QH
					More data for this Ligand-Target Pair