BDBM50304404 10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2,7}.0^{16,20}]henicosa-1(14),2(7),3,5,15,20-hexaene::CHEMBL610449

SMILES: CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1

InChI Key: InChIKey=IPSSDOFRDHFANX-UHFFFAOYSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50304404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50304404 (10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2...) Show SMILES CN1CCCc2cc3OCOc3cc2-c2ccccc2CC1 Show InChI InChI=1S/C19H21NO2/c1-20-9-4-6-15-11-18-19(22-13-21-18)12-17(15)16-7-3-2-5-14(16)8-10-20/h2-3,5,7,11-12H,4,6,8-10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells by scintillation counting				Bioorg Med Chem 17: 6898-907 (2009) Article DOI: 10.1016/j.bmc.2009.08.028 BindingDB Entry DOI: 10.7270/Q2SB46P5
					More data for this Ligand-Target Pair