BDBM50311299 5-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide::CHEMBL1080957

SMILES: Clc1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1

InChI Key: InChIKey=OQDMQIQQRYKUIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 3 (Homo sapiens (Human))	BDBM50311299 (5-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...) Show SMILES Clc1ccn2ncc(C(=O)Nc3ccccc3Cl)c2c1 Show InChI InChI=1S/C14H9Cl2N3O/c15-9-5-6-19-13(7-9)10(8-17-19)14(20)18-12-4-2-1-3-11(12)16/h1-8H,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...				Bioorg Med Chem Lett 19: 6122-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.010 BindingDB Entry DOI: 10.7270/Q2T43T66
					More data for this Ligand-Target Pair