BDBM50311317 CHEMBL1077740::N-(2-chlorophenyl)-6-(4-hydroxypiperidin-4-yl)imidazo[1,2-a]pyridine-3-carboxamide

SMILES: OC1(CCNCC1)c1ccc2ncc(C(=O)Nc3ccccc3Cl)n2c1

InChI Key: InChIKey=NFPDLYRGXRIUTG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 3 (EPHB3) (Homo sapiens (Human))	BDBM50311317 (CHEMBL1077740 | N-(2-chlorophenyl)-6-(4-hydroxypip...) Show SMILES OC1(CCNCC1)c1ccc2ncc(C(=O)Nc3ccccc3Cl)n2c1 Show InChI InChI=1S/C19H19ClN4O2/c20-14-3-1-2-4-15(14)23-18(25)16-11-22-17-6-5-13(12-24(16)17)19(26)7-9-21-10-8-19/h1-6,11-12,21,26H,7-10H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...				Bioorg Med Chem Lett 19: 6122-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.010 BindingDB Entry DOI: 10.7270/Q2T43T66
					More data for this Ligand-Target Pair