null

SMILES: Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O

InChI Key: InChIKey=BONJIRURBUJMTG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50312425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312425 (2-(4-((4-(4-(Cyclopentyloxy)phenyl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C31H28F3NO6S/c1-19-16-25(14-15-26(19)39-18-28(36)37)38-17-27-35-29(20-6-10-23(11-7-20)40-22-4-2-3-5-22)30(42-27)21-8-12-24(13-9-21)41-31(32,33)34/h6-16,22H,2-5,17-18H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain by FRET assay				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312425 (2-(4-((4-(4-(Cyclopentyloxy)phenyl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C31H28F3NO6S/c1-19-16-25(14-15-26(19)39-18-28(36)37)38-17-27-35-29(20-6-10-23(11-7-20)40-22-4-2-3-5-22)30(42-27)21-8-12-24(13-9-21)41-31(32,33)34/h6-16,22H,2-5,17-18H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312425 (2-(4-((4-(4-(Cyclopentyloxy)phenyl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C31H28F3NO6S/c1-19-16-25(14-15-26(19)39-18-28(36)37)38-17-27-35-29(20-6-10-23(11-7-20)40-22-4-2-3-5-22)30(42-27)21-8-12-24(13-9-21)41-31(32,33)34/h6-16,22H,2-5,17-18H2,1H3,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312425 (2-(4-((4-(4-(Cyclopentyloxy)phenyl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C31H28F3NO6S/c1-19-16-25(14-15-26(19)39-18-28(36)37)38-17-27-35-29(20-6-10-23(11-7-20)40-22-4-2-3-5-22)30(42-27)21-8-12-24(13-9-21)41-31(32,33)34/h6-16,22H,2-5,17-18H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50312425 (2-(4-((4-(4-(Cyclopentyloxy)phenyl)-5-(4-(trifluor...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(OC3CCCC3)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C31H28F3NO6S/c1-19-16-25(14-15-26(19)39-18-28(36)37)38-17-27-35-29(20-6-10-23(11-7-20)40-22-4-2-3-5-22)30(42-27)21-8-12-24(13-9-21)41-31(32,33)34/h6-16,22H,2-5,17-18H2,1H3,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at mouse PPARdelta by FRET assay				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair