BDBM50312650 5,4'-dihydroxyflavone::5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL484662

SMILES: Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1

InChI Key: InChIKey=STYVAERQLVJTRI-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipoxygenase-1 (Glycine max (soybean))	BDBM50312650 (5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...) Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1 Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Mixed noncompetitive type inhibition of soybean LOX-1 using linoleic acid as substrate preincubated for 5 mins followed by substrate addition by Line...				Eur J Med Chem 72: 137-45 (2014) Article DOI: 10.1016/j.ejmech.2013.11.030 BindingDB Entry DOI: 10.7270/Q27H1M2P
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50312650 (5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...) Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1 Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Meijo University Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay				Bioorg Med Chem 21: 2968-74 (2013) Article DOI: 10.1016/j.bmc.2013.03.060 BindingDB Entry DOI: 10.7270/Q2FT8NFN
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50312650 (5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...) Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1 Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	851	n/a	n/a	n/a	n/a	n/a	n/a
Meijo University Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor LBD expressed in human MDA-kb2 cells by luciferase reporter gene assay				Bioorg Med Chem 21: 2968-74 (2013) Article DOI: 10.1016/j.bmc.2013.03.060 BindingDB Entry DOI: 10.7270/Q2FT8NFN
					More data for this Ligand-Target Pair
Sialidase 2 (Homo sapiens (Human))	BDBM50312650 (5,4'-dihydroxyflavone | 5-hydroxy-2-(4-hydroxyphen...) Show SMILES Oc1ccc(cc1)-c1cc(O)c2c(cccc2=O)o1 Show InChI InChI=1S/C15H10O4/c16-10-6-4-9(5-7-10)14-8-12(18)15-11(17)2-1-3-13(15)19-14/h1-8,16,18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assay				Bioorg Med Chem 18: 1633-40 (2010) Article DOI: 10.1016/j.bmc.2009.12.062 BindingDB Entry DOI: 10.7270/Q26110F1
					More data for this Ligand-Target Pair