BDBM50313094 5-fluoro-6-[(2-aminoimidazol-1-yl)methyl]uracil::CHEMBL1080896

SMILES: Nc1nccn1Cc1[nH]c(=O)[nH]c(=O)c1F

InChI Key: InChIKey=SFEMKOUUPCFITA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine Phosphorylase (TP) (Homo sapiens (Human))	BDBM50313094 (5-fluoro-6-[(2-aminoimidazol-1-yl)methyl]uracil | ...) Show SMILES Nc1nccn1Cc1[nH]c(=O)[nH]c(=O)c1F Show InChI InChI=1S/C8H8FN5O2/c9-5-4(12-8(16)13-6(5)15)3-14-2-1-11-7(14)10/h1-2H,3H2,(H2,10,11)(H2,12,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University at Buffalo Curated by ChEMBL					Assay Description Inhibition of human thymidine phosphorylase				Bioorg Med Chem Lett 20: 1648-51 (2010) Article DOI: 10.1016/j.bmcl.2010.01.076 BindingDB Entry DOI: 10.7270/Q26T0MSH
					More data for this Ligand-Target Pair