BDBM50314789 CHEMBL1088796::N-cyclopropyl-3-(1-(2-fluorophenyl)phthalazin-6-yl)-4-methylbenzamide

SMILES: Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1

InChI Key: InChIKey=WAKUIUNRDNSMQR-UHFFFAOYSA-N

Data: 4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50314789 (CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1 Show InChI InChI=1S/C25H20FN3O/c1-15-6-7-17(25(30)28-19-9-10-19)13-22(15)16-8-11-20-18(12-16)14-27-29-24(20)21-4-2-3-5-23(21)26/h2-8,11-14,19H,9-10H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to p38alpha by scintillation proximity assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50314789 (CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1 Show InChI InChI=1S/C25H20FN3O/c1-15-6-7-17(25(30)28-19-9-10-19)13-22(15)16-8-11-20-18(12-16)14-27-29-24(20)21-4-2-3-5-23(21)26/h2-8,11-14,19H,9-10H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to c-Kit by scintillation proximity assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50314789 (CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1 Show InChI InChI=1S/C25H20FN3O/c1-15-6-7-17(25(30)28-19-9-10-19)13-22(15)16-8-11-20-18(12-16)14-27-29-24(20)21-4-2-3-5-23(21)26/h2-8,11-14,19H,9-10H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to Lck by scintillation proximity assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50314789 (CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...) Show SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1 Show InChI InChI=1S/C25H20FN3O/c1-15-6-7-17(25(30)28-19-9-10-19)13-22(15)16-8-11-20-18(12-16)14-27-29-24(20)21-4-2-3-5-23(21)26/h2-8,11-14,19H,9-10H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to Kdr by scintillation proximity assay				J Med Chem 53: 2973-85 (2010) Article DOI: 10.1021/jm100095x BindingDB Entry DOI: 10.7270/Q2FX79MD
					More data for this Ligand-Target Pair