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BDBM50321266 4-chloro-N-(2-(2-methoxy-4-(prop-1-enyl)phenoxy)ethyl)benzamide::CHEMBL1163690

SMILES: COc1cc(\C=C\C)ccc1OCCNC(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=KADMZEPDMZDBKH-ONEGZZNKSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321266   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Schizosaccharomyces pombe)
BDBM50321266
PNG
(4-chloro-N-(2-(2-methoxy-4-(prop-1-enyl)phenoxy)et...)
Show SMILES COc1cc(\C=C\C)ccc1OCCNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClNO3/c1-3-4-14-5-10-17(18(13-14)23-2)24-12-11-21-19(22)15-6-8-16(20)9-7-15/h3-10,13H,11-12H2,1-2H3,(H,21,22)/b4-3+
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a



Instituto Polit£cnico Nacional (IPN)

Curated by ChEMBL


Assay Description
Inhibition of Schizosaccharomyces pombe HMG-CoA reductase by spectrophotometry


Bioorg Med Chem 18: 4238-48 (2010)


Article DOI: 10.1016/j.bmc.2010.04.096
BindingDB Entry DOI: 10.7270/Q2KW5H0Z
More data for this
Ligand-Target Pair