null
SMILES: Cc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2ccccn2)CC1
InChI Key: InChIKey=GXAJAEYMTGMWDK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50322371 (1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hex...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Displacement of [3H]8OH-DPAT from 5HT1A receptor in rat CRL:CD(SD)BR-COBS hippocampus by scintillation spectrometry | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50322371 (1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hex...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometry | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50322371 (1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hex...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50322371 (1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hex...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometry | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50322371 (1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita di Siena Curated by ChEMBL | Assay Description Binding affinity to human ERG expressed in HEK293 cells | J Med Chem 53: 4803-7 (2010) Article DOI: 10.1021/jm100294b BindingDB Entry DOI: 10.7270/Q28P60QP | |||||||||||
More data for this Ligand-Target Pair |