BDBM50323327 CHEMBL4171772

SMILES: Clc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c(Cl)c1

InChI Key: InChIKey=XJCXDJMNZIOJDP-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50323327 (CHEMBL4171772) Show SMILES Clc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c(Cl)c1 Show InChI InChI=1S/C14H8BrCl2N5O/c15-7-1-3-10(13-19-21-22-20-13)12(5-7)18-14(23)9-4-2-8(16)6-11(9)17/h1-6H,(H,18,23)(H,19,20,21,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at GPR35 in human HT-29 cells by dynamic mass redistribution assay				ACS Med Chem Lett 9: 422-427 (2018) Article DOI: 10.1021/acsmedchemlett.7b00510 BindingDB Entry DOI: 10.7270/Q2GB26K8
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50323327 (CHEMBL4171772) Show SMILES Clc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c(Cl)c1 Show InChI InChI=1S/C14H8BrCl2N5O/c15-7-1-3-10(13-19-21-22-20-13)12(5-7)18-14(23)9-4-2-8(16)6-11(9)17/h1-6H,(H,18,23)(H,19,20,21,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at human GPR35 assessed as induction of beta-arrestin recruitment				ACS Med Chem Lett 9: 422-427 (2018) Article DOI: 10.1021/acsmedchemlett.7b00510 BindingDB Entry DOI: 10.7270/Q2GB26K8
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50323327 (CHEMBL4171772) Show SMILES Clc1ccc(C(=O)Nc2cc(Br)ccc2-c2nnn[nH]2)c(Cl)c1 Show InChI InChI=1S/C14H8BrCl2N5O/c15-7-1-3-10(13-19-21-22-20-13)12(5-7)18-14(23)9-4-2-8(16)6-11(9)17/h1-6H,(H,18,23)(H,19,20,21,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Desensitization of GPR35 in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution pretreated for 1 hr followed by...				ACS Med Chem Lett 9: 422-427 (2018) Article DOI: 10.1021/acsmedchemlett.7b00510 BindingDB Entry DOI: 10.7270/Q2GB26K8
					More data for this Ligand-Target Pair