BDBM50326152 8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan-4-carboxylic acid::CHEMBL1242552

SMILES: OC(=O)c1cccc2c3cc(ccc3oc12)-c1csc(n1)-c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=FHNSBIYBHXTXGH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50326152 (8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...) Show SMILES OC(=O)c1cccc2c3cc(ccc3oc12)-c1csc(n1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C22H12N2O5S/c25-22(26)16-3-1-2-15-17-10-13(6-9-19(17)29-20(15)16)18-11-30-21(23-18)12-4-7-14(8-5-12)24(27)28/h1-11H,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50326152 (8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...) Show SMILES OC(=O)c1cccc2c3cc(ccc3oc12)-c1csc(n1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C22H12N2O5S/c25-22(26)16-3-1-2-15-17-10-13(6-9-19(17)29-20(15)16)18-11-30-21(23-18)12-4-7-14(8-5-12)24(27)28/h1-11H,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant LAR after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50326152 (8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...) Show SMILES OC(=O)c1cccc2c3cc(ccc3oc12)-c1csc(n1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C22H12N2O5S/c25-22(26)16-3-1-2-15-17-10-13(6-9-19(17)29-20(15)16)18-11-30-21(23-18)12-4-7-14(8-5-12)24(27)28/h1-11H,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant TCPTP after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair