BDBM50326236 CHEMBL1243074::N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-yl)-propyl]-piperidin-4-yl}-2-phenyl-acetamide

SMILES: Fc1cccc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c12

InChI Key: InChIKey=CYBGLMVMPDDUMC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50326236 (CHEMBL1243074 | N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydr...) Show SMILES Fc1cccc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c12 Show InChI InChI=1S/C25H30FN3O2/c26-22-9-4-8-20-10-11-24(31)29(25(20)22)15-5-14-28-16-12-21(13-17-28)27-23(30)18-19-6-2-1-3-7-19/h1-4,6-9,21H,5,10-18H2,(H,27,30)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay				J Med Chem 53: 6386-97 (2010) Article DOI: 10.1021/jm100697g BindingDB Entry DOI: 10.7270/Q2765G9K
					More data for this Ligand-Target Pair