BDBM50328383 CHEMBL1258709::ethyl 6-(3-benzyl-1,2,4-oxadiazol-5-yl)-2-morpholino-4-phenyl-7-propylpyrrolo[1,2-b]pyridazine-5-carboxylate

SMILES: CCCc1c(-c2nc(Cc3ccccc3)no2)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1

InChI Key: InChIKey=SKEBJINBVARVMV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50328383 (CHEMBL1258709 | ethyl 6-(3-benzyl-1,2,4-oxadiazol-...) Show SMILES CCCc1c(-c2nc(Cc3ccccc3)no2)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C32H33N5O4/c1-3-11-25-28(31-33-26(35-41-31)20-22-12-7-5-8-13-22)29(32(38)40-4-2)30-24(23-14-9-6-10-15-23)21-27(34-37(25)30)36-16-18-39-19-17-36/h5-10,12-15,21H,3-4,11,16-20H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs				Bioorg Med Chem Lett 20: 6030-3 (2010) Article DOI: 10.1016/j.bmcl.2010.08.066 BindingDB Entry DOI: 10.7270/Q2RV0NX1
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50328383 (CHEMBL1258709 | ethyl 6-(3-benzyl-1,2,4-oxadiazol-...) Show SMILES CCCc1c(-c2nc(Cc3ccccc3)no2)c(C(=O)OCC)c2c(cc(nn12)N1CCOCC1)-c1ccccc1 Show InChI InChI=1S/C32H33N5O4/c1-3-11-25-28(31-33-26(35-41-31)20-22-12-7-5-8-13-22)29(32(38)40-4-2)30-24(23-14-9-6-10-15-23)21-27(34-37(25)30)36-16-18-39-19-17-36/h5-10,12-15,21H,3-4,11,16-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 mins				Bioorg Med Chem Lett 20: 6030-3 (2010) Article DOI: 10.1016/j.bmcl.2010.08.066 BindingDB Entry DOI: 10.7270/Q2RV0NX1
					More data for this Ligand-Target Pair