BDBM50328948 (4-isopropylpiperazin-1-yl)(3-(piperidine-1-carbonyl)benzo[b]thiophen-5-yl)methanone::CHEMBL1270172

SMILES: CC(C)N1CCN(CC1)C(=O)c1ccc2scc(C(=O)N3CCCCC3)c2c1

InChI Key: InChIKey=UYWZQGGEESMROT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50328948 ((4-isopropylpiperazin-1-yl)(3-(piperidine-1-carbon...) Show SMILES CC(C)N1CCN(CC1)C(=O)c1ccc2scc(C(=O)N3CCCCC3)c2c1 Show InChI InChI=1S/C22H29N3O2S/c1-16(2)23-10-12-25(13-11-23)21(26)17-6-7-20-18(14-17)19(15-28-20)22(27)24-8-4-3-5-9-24/h6-7,14-16H,3-5,8-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells after 1 hr by fluid scintillation co...				Bioorg Med Chem Lett 20: 6226-30 (2010) Article DOI: 10.1016/j.bmcl.2010.08.103 BindingDB Entry DOI: 10.7270/Q2CF9QB3
					More data for this Ligand-Target Pair