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SMILES: CNC(=O)c1csc2cc(Oc3ccnc4cc(sc34)C3=NCCN3C)ccc12

InChI Key: InChIKey=CDHZKYJMFPYMBV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331091   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50331091
PNG
(AG-028262 | CHEMBL1289925 | N-methyl-6-(2-(1-methy...)
Show SMILES CNC(=O)c1csc2cc(Oc3ccnc4cc(sc34)C3=NCCN3C)ccc12 |t:22|
Show InChI InChI=1S/C21H18N4O2S2/c1-22-21(26)14-11-28-17-9-12(3-4-13(14)17)27-16-5-6-23-15-10-18(29-19(15)16)20-24-7-8-25(20)2/h3-6,9-11H,7-8H2,1-2H3,(H,22,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.340n/an/an/an/an/an/a



Konkuk University

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assay

Eur J Med Chem 45: 5420-7 (2010)


Article DOI: 10.1016/j.ejmech.2010.09.002
BindingDB Entry DOI: 10.7270/Q2TX3FMZ
More data for this
Ligand-Target Pair