BDBM50331183 (S)-2-cinnamamido-N8-hydroxy-N1-(quinolin-8-yl)octanediamide::CHEMBL220692

SMILES: ONC(=O)CCCCC[C@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=NIGUOYSXBDUJSL-QWYDYZLZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone Deacetylase (pfHDAC-1) (Plasmodium falciparum (isolate 3D7))	BDBM50331183 ((S)-2-cinnamamido-N8-hydroxy-N1-(quinolin-8-yl)oct...) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)\C=C\c1ccccc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C26H28N4O4/c31-23(17-16-19-9-3-1-4-10-19)28-22(13-5-2-6-15-24(32)30-34)26(33)29-21-14-7-11-20-12-8-18-27-25(20)21/h1,3-4,7-12,14,16-18,22,34H,2,5-6,13,15H2,(H,28,31)(H,29,33)(H,30,32)/b17-16+/t22-/m0/s1	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum 3D7 HDAC1 in infected-human erythrocytes assessed as histone H4 hyperacetylation after 1.5 hrs by SDS-PAGE analys...				Bioorg Med Chem Lett 20: 7080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.096 BindingDB Entry DOI: 10.7270/Q22B8Z8W
					More data for this Ligand-Target Pair