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SMILES: CC1=CCCN(CCCC#Cc2cc(cc(c2)C#CCCCN2CCC=C(C)C2)C#CCCCN2CCC=C(C)C2)C1

InChI Key: InChIKey=DWFYNNQWDXKIDX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334466   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-6


(Rattus norvegicus)		BDBM50334466
PNG
(1,3,5-tris(5-(3-methyl-5,6-dihydropyridin-1(2H)-yl...)
Show SMILES CC1=CCCN(CCCC#Cc2cc(cc(c2)C#CCCCN2CCC=C(C)C2)C#CCCCN2CCC=C(C)C2)C1 |t:1,26,39|
Show InChI InChI=1S/C39H51N3/c1-34-16-13-25-40(31-34)22-10-4-7-19-37-28-38(20-8-5-11-23-41-26-14-17-35(2)32-41)30-39(29-37)21-9-6-12-24-42-27-15-18-36(3)33-42/h16-18,28-30H,4-6,10-15,22-27,31-33H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.22n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine release

Bioorg Med Chem Lett 21: 88-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.070
BindingDB Entry DOI: 10.7270/Q2VT1SDX
More data for this
Ligand-Target Pair