BindingDB PrimarySearch

BDBM50335374 (3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione::CHEMBL1651521::CHEMBL1651522

SMILES: COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1

InChI Key: InChIKey=QMEZKJBCLUGJTN-WFASDCNBSA-N

Data: 38 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50335374
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p38alpha by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of TYK2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of cKIT by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of INSR by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ROCK2 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ALK by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	763	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ALK by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EPHB4 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ERK2 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RET by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	673	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of cKIT by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of LCK by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of MNK2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of TYK2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ERK2 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EPHB4 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of RET by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Aurora A kinase by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Axl by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of BTK by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of CDK2A by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ZAP70 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EPHA4 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FGFR3 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HER2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HGFR by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of IGF1R by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of JAK1 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of JAK2 by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of JAK3 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PDK1 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PKAalpha by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase N1 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PKN1 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase N2 (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PKN2 by Caliper mobility shift assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50335374 ((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of LCK by TR-FRET based LanthaScreen assay				ACS Med Chem Lett 2: 22-27 (2011) Article DOI: 10.1021/ml1001807 BindingDB Entry DOI: 10.7270/Q2542NWT
TBA Curated by ChEMBL					More data for this Ligand-Target Pair