BDBM50335476 (S)-4-(3-(2-((1-(2-(2-(2-(4-((4-(1-acetyl-6-biphenyl-4-ylcarboxamido-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-4-yl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methylamino)-2-oxoethylamino)phenyl)-5-amino-N-tert-butyl-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide::CHEMBL1651821

SMILES: CSc1nc(-c2cccc(NCC(=O)NCc3cn(CCOCCOCCn4cc(COc5ccc(cc5)[C@]5(C)CC(C)(C)N(C(C)=O)c6ccc(NC(=O)c7ccc(cc7)-c7ccccc7)cc56)nn4)nn3)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C

InChI Key: InChIKey=LPTFUKMDWXCPBR-FZWUFXCXSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50335476 ((S)-4-(3-(2-((1-(2-(2-(2-(4-((4-(1-acetyl-6-biphen...) Show SMILES CSc1nc(-c2cccc(NCC(=O)NCc3cn(CCOCCOCCn4cc(COc5ccc(cc5)[C@]5(C)CC(C)(C)N(C(C)=O)c6ccc(NC(=O)c7ccc(cc7)-c7ccccc7)cc56)nn4)nn3)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C |r| Show InChI InChI=1S/C65H72N14O7S2/c1-41(80)79-53-26-23-48(69-59(82)44-19-17-43(18-20-44)42-13-10-9-11-14-42)34-52(53)65(7,40-64(79,5)6)46-21-24-51(25-22-46)86-39-50-38-78(76-74-50)28-30-85-32-31-84-29-27-77-37-49(73-75-77)35-68-54(81)36-67-47-16-12-15-45(33-47)57-55-56(66)58(60(83)72-63(2,3)4)88-61(55)71-62(70-57)87-8/h9-26,33-34,37-38,67H,27-32,35-36,39-40,66H2,1-8H3,(H,68,81)(H,69,82)(H,72,83)/t65-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene...				ACS Med Chem Lett 2: 85-89 (2011) Article DOI: 10.1021/ml100229v BindingDB Entry DOI: 10.7270/Q2RV0NZG
					More data for this Ligand-Target Pair