BDBM50337186 4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(5-m-tolylpyridin-2-yl)piperidin-4-yl)methyl)benzamide::CHEMBL1684863

SMILES: CC(C)c1cc(cc2nc(oc12)-c1ccc(cc1)C(=O)NCC1CCN(CC1)c1ccc(cn1)-c1cccc(C)c1)C#N

InChI Key: InChIKey=SBRJMGVDMGKNPW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50337186 (4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(...) Show SMILES CC(C)c1cc(cc2nc(oc12)-c1ccc(cc1)C(=O)NCC1CCN(CC1)c1ccc(cn1)-c1cccc(C)c1)C#N Show InChI InChI=1S/C36H35N5O2/c1-23(2)31-18-26(20-37)19-32-34(31)43-36(40-32)28-9-7-27(8-10-28)35(42)39-21-25-13-15-41(16-14-25)33-12-11-30(22-38-33)29-6-4-5-24(3)17-29/h4-12,17-19,22-23,25H,13-16,21H2,1-3H3,(H,39,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem Lett 21: 1890-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.090 BindingDB Entry DOI: 10.7270/Q2NG4QW6
					More data for this Ligand-Target Pair