Found 8 hits for monomerid = 50338201 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of FLT4 |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Macrophage colony stimulating factor receptor
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 622 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of CSF1R |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of RET |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of FLT3 |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 513 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of KIT |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of PDGFRalpha |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50338201
(1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...)Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+ | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development LLC
Curated by ChEMBL
| Assay Description Inhibition of FLT1 |
Bioorg Med Chem Lett 21: 1815-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK |
More data for this Ligand-Target Pair | |