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SMILES: COc1ccc(cc1F)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(C)n3)nc12

InChI Key: InChIKey=NCUDSKLYBDQTIW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50340613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50340613 (8-(3-fluoro-4-methoxyphenyl)-N-(4-(3-methyl-1H-1,2...) Show SMILES COc1ccc(cc1F)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(C)n3)nc12 Show InChI InChI=1S/C24H19FN6O/c1-15-27-14-31(30-15)19-9-7-18(8-10-19)28-24-26-13-17-4-3-5-20(23(17)29-24)16-6-11-22(32-2)21(25)12-16/h3-14H,1-2H3,(H,26,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of c-Jun				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50340613 (8-(3-fluoro-4-methoxyphenyl)-N-(4-(3-methyl-1H-1,2...) Show SMILES COc1ccc(cc1F)-c1cccc2cnc(Nc3ccc(cc3)-n3cnc(C)n3)nc12 Show InChI InChI=1S/C24H19FN6O/c1-15-27-14-31(30-15)19-9-7-18(8-10-19)28-24-26-13-17-4-3-5-20(23(17)29-24)16-6-11-22(32-2)21(25)12-16/h3-14H,1-2H3,(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair