BDBM50342686 1-(5-chloropyridin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine::CHEMBL1771088

SMILES: CS(=O)(=O)c1ccc(cc1)N1CCC(CC1)C1CCN(CC1)c1ccc(Cl)cn1

InChI Key: InChIKey=CQGOOXRESMDIBQ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50342686 (1-(5-chloropyridin-2-yl)-1'-(4-(methylsulfonyl)phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(CC1)C1CCN(CC1)c1ccc(Cl)cn1 Show InChI InChI=1S/C22H28ClN3O2S/c1-29(27,28)21-5-3-20(4-6-21)25-12-8-17(9-13-25)18-10-14-26(15-11-18)22-7-2-19(23)16-24-22/h2-7,16-18H,8-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	131	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50342686 (1-(5-chloropyridin-2-yl)-1'-(4-(methylsulfonyl)phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(CC1)C1CCN(CC1)c1ccc(Cl)cn1 Show InChI InChI=1S/C22H28ClN3O2S/c1-29(27,28)21-5-3-20(4-6-21)25-12-8-17(9-13-25)18-10-14-26(15-11-18)22-7-2-19(23)16-24-22/h2-7,16-18H,8-15H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair