BDBM50347705 CHEMBL1802461

SMILES: Oc1ccc(\C=C2/CN(Cc3cccc(Cl)c3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br

InChI Key: InChIKey=SGFUCORRJXWOBJ-PQEHHWQQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50347705 (CHEMBL1802461) Show SMILES Oc1ccc(\C=C2/CN(Cc3cccc(Cl)c3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br Show InChI InChI=1S/C26H20Br2ClNO3/c27-22-11-16(4-6-24(22)31)8-19-14-30(13-18-2-1-3-21(29)10-18)15-20(26(19)33)9-17-5-7-25(32)23(28)12-17/h1-12,31-32H,13-15H2/b19-8+,20-9+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas MD Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of CARM1-mediated methylation of PABP1 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine				J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F
					More data for this Ligand-Target Pair
SET domain-containing protein 7/9 (Set7/9) (Homo sapiens (Human))	BDBM50347705 (CHEMBL1802461) Show SMILES Oc1ccc(\C=C2/CN(Cc3cccc(Cl)c3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br Show InChI InChI=1S/C26H20Br2ClNO3/c27-22-11-16(4-6-24(22)31)8-19-14-30(13-18-2-1-3-21(29)10-18)15-20(26(19)33)9-17-5-7-25(32)23(28)12-17/h1-12,31-32H,13-15H2/b19-8+,20-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas MD Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of SET7-mediated methylation of histone H3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine				J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F
					More data for this Ligand-Target Pair
Protein-arginine N-methyltransferase 1 (Homo sapiens (Human))	BDBM50347705 (CHEMBL1802461) Show SMILES Oc1ccc(\C=C2/CN(Cc3cccc(Cl)c3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br Show InChI InChI=1S/C26H20Br2ClNO3/c27-22-11-16(4-6-24(22)31)8-19-14-30(13-18-2-1-3-21(29)10-18)15-20(26(19)33)9-17-5-7-25(32)23(28)12-17/h1-12,31-32H,13-15H2/b19-8+,20-9+	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas MD Anderson Cancer Center Curated by ChEMBL					Assay Description Inhibition of PRMT1-mediated methylation of NPL3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionine				J Med Chem 54: 4928-32 (2011) Article DOI: 10.1021/jm200453n BindingDB Entry DOI: 10.7270/Q2MK6D7F
					More data for this Ligand-Target Pair