BDBM50350758 CHEMBL1818433
SMILES: OC[C@H]1CNC[C@@H](O)[C@H]1O
InChI Key: InChIKey=QPYJXFZUIJOGNX-PBXRRBTRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-galactosidase (Escherichia coli) | BDBM50350758 (CHEMBL1818433) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of Escherichia coli lacZ beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed b... | Bioorg Med Chem Lett 26: 1438-42 (2016) BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Bos taurus (Bovine)) | BDBM50350758 (CHEMBL1818433) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of bovine liver beta-galactosidase using 4-nitrophenyl-beta-D-galactopyranoside as substrate preincubated up to 5 mins followed by substra... | Bioorg Med Chem Lett 26: 1438-42 (2016) BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-galactosidase A (Homo sapiens (Human)) | BDBM50350758 (CHEMBL1818433) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | >2.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Graz University of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min... | Bioorg Med Chem Lett 26: 1438-42 (2016) BindingDB Entry DOI: 10.7270/Q2HQ41SR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
β-galactosidase (Bos taurus (Bovine)) | BDBM50350758 (CHEMBL1818433) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometry | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50350758 (CHEMBL1818433) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans& CNRS Curated by ChEMBL | Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E | Eur J Med Chem 126: 160-170 (2017) Article DOI: 10.1016/j.ejmech.2016.09.095 BindingDB Entry DOI: 10.7270/Q21G0PHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50350758 (CHEMBL1818433) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat... | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50350758 (CHEMBL1818433) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans& CNRS Curated by ChEMBL | Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E | Eur J Med Chem 126: 160-170 (2017) Article DOI: 10.1016/j.ejmech.2016.09.095 BindingDB Entry DOI: 10.7270/Q21G0PHR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactase-glycosylceramidase (Rattus norvegicus) | BDBM50350758 (CHEMBL1818433) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometry | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucosylceramidase (Bos taurus) | BDBM50350758 (CHEMBL1818433) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ... | Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW | |||||||||||
More data for this Ligand-Target Pair |