BDBM50357760 CHEMBL1916397

SMILES: CN(C)c1ccc(CNCCC(Cc2ccccc2)c2ccc3OCOc3c2)cc1

InChI Key: InChIKey=OVRCVYWNUUCNIN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase receptor (uPAR) (Homo sapiens (Human))	BDBM50357760 (CHEMBL1916397) Show SMILES CN(C)c1ccc(CNCCC(Cc2ccccc2)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C26H30N2O2/c1-28(2)24-11-8-21(9-12-24)18-27-15-14-23(16-20-6-4-3-5-7-20)22-10-13-25-26(17-22)30-19-29-25/h3-13,17,23,27H,14-16,18-19H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Displacement of AE417-FAM peptide from human uPAR expressed in drosophila S2 cells by fluorescence polarization assay				J Med Chem 54: 7193-205 (2011) Article DOI: 10.1021/jm200782y BindingDB Entry DOI: 10.7270/Q28K79H2
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50357760 (CHEMBL1916397) Show SMILES CN(C)c1ccc(CNCCC(Cc2ccccc2)c2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C26H30N2O2/c1-28(2)24-11-8-21(9-12-24)18-27-15-14-23(16-20-6-4-3-5-7-20)22-10-13-25-26(17-22)30-19-29-25/h3-13,17,23,27H,14-16,18-19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human MMP-9 activity in human MDA-MB-231 cells assessed as ECM degradation after 24 hrs by gelatin zymography assay				J Med Chem 54: 7193-205 (2011) Article DOI: 10.1021/jm200782y BindingDB Entry DOI: 10.7270/Q28K79H2
					More data for this Ligand-Target Pair