BDBM50358184 CHEMBL1921954

SMILES: Fc1cc(ccc1NC(=O)c1ccccn1)N1S(=O)(=O)c2ccccc2S1(=O)=O

InChI Key: InChIKey=LIFOQDABDOAYFP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50358184 (CHEMBL1921954) Show SMILES Fc1cc(ccc1NC(=O)c1ccccn1)N1S(=O)(=O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C18H12FN3O5S2/c19-13-11-12(8-9-14(13)21-18(23)15-5-3-4-10-20-15)22-28(24,25)16-6-1-2-7-17(16)29(22,26)27/h1-11H,(H,21,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay				J Med Chem 54: 7639-47 (2011) Article DOI: 10.1021/jm200956q BindingDB Entry DOI: 10.7270/Q25Q4WHD
					More data for this Ligand-Target Pair