BDBM50359367 CHEMBL1929388

SMILES: Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1

InChI Key: InChIKey=WFOKSQKLWVYFPZ-HNNXBMFYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50359367 (CHEMBL1929388) Show SMILES Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 |r| Show InChI InChI=1S/C20H27N7O2/c1-13-8-17-22-10-16(14(2)27(17)25-13)19(29)23-12-20(3,4)24-11-18(28)26-7-5-6-15(26)9-21/h8,10,15,24H,5-7,11-12H2,1-4H3,(H,23,29)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-4 using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50359367 (CHEMBL1929388) Show SMILES Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 |r| Show InChI InChI=1S/C20H27N7O2/c1-13-8-17-22-10-16(14(2)27(17)25-13)19(29)23-12-20(3,4)24-11-18(28)26-7-5-6-15(26)9-21/h8,10,15,24H,5-7,11-12H2,1-4H3,(H,23,29)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-9 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50359367 (CHEMBL1929388) Show SMILES Cc1cc2ncc(C(=O)NCC(C)(C)NCC(=O)N3CCC[C@H]3C#N)c(C)n2n1 |r| Show InChI InChI=1S/C20H27N7O2/c1-13-8-17-22-10-16(14(2)27(17)25-13)19(29)23-12-20(3,4)24-11-18(28)26-7-5-6-15(26)9-21/h8,10,15,24H,5-7,11-12H2,1-4H3,(H,23,29)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair