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SMILES: CCn1c2ccccc2c2cc(CN3CCC4(CC3)[C@H](O)[C@@H](NC(C)=O)c3ccccc43)ccc12

InChI Key: InChIKey=WLKCGASCIGZQCK-URLMMPGGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360700   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360700
PNG
(CHEMBL1934119)
Show SMILES CCn1c2ccccc2c2cc(CN3CCC4(CC3)[C@H](O)[C@@H](NC(C)=O)c3ccccc43)ccc12 |r|
Show InChI InChI=1S/C30H33N3O2/c1-3-33-26-11-7-5-8-22(26)24-18-21(12-13-27(24)33)19-32-16-14-30(15-17-32)25-10-6-4-9-23(25)28(29(30)35)31-20(2)34/h4-13,18,28-29,35H,3,14-17,19H2,1-2H3,(H,31,34)/t28-,29+/m0/s1
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n/an/a 100n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair