Found 23 hits for monomerid = 50362867 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay |
J Med Chem 62: 9488-9520 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00864 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay |
J Med Chem 62: 9488-9520 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00864 |
More data for this Ligand-Target Pair | |
Dopamine receptor
(RAT) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]DOI from human 5HT2A receptor after 1 hr by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H] 8-OH-DPAT from human 5-HT1A receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Ketanserin from human 5-HT2A receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
D(1B) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Pyrilamine from human histamine H1 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Citalopram from human Serotonin transporter by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
Dopamine receptor
(RAT) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 248 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 317 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 497 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]GBR12935 from human dopamine transporter by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT7 receptor by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Nisoxetine from human Norepinephrine transporter by liquid scintillation counting |
Bioorg Med Chem Lett 24: 4294-7 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.018 BindingDB Entry DOI: 10.7270/Q2222WF8 |
More data for this Ligand-Target Pair | |
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
(Rattus norvegicus (Rat)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from rat 5HT2C receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay |
J Med Chem 62: 9488-9520 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00864 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362867
(CHEMBL1940403)Show InChI InChI=1S/C20H23ClFNOS/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay |
J Med Chem 62: 9488-9520 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00864 |
More data for this Ligand-Target Pair | |