Found 38 hits for monomerid = 50371970 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by ChEMBL
| Assay Description Inhibition of human carboxylesterase 1 after 24 hrs |
Bioorg Med Chem 17: 149-64 (2008)
Article DOI: 10.1016/j.bmc.2008.11.008 BindingDB Entry DOI: 10.7270/Q2JH3NFK |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 191 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University
Curated by ChEMBL
| Assay Description Inhibition of human carboxylesterase 1 after 5 mins |
Bioorg Med Chem 17: 149-64 (2008)
Article DOI: 10.1016/j.bmc.2008.11.008 BindingDB Entry DOI: 10.7270/Q2JH3NFK |
More data for this Ligand-Target Pair | |
Juvenile hormone esterase (JHE)
(Manduca sexta (Moths)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Manduca sexta juvenile hormone esterase |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxylesterase 1 after 5 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxylesterase 1 after 15 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Carboxylesterase 2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxylesterase 2 after 5 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Carboxylesterase 2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxylesterase 2 after 15 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH after 5 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH after 15 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Juvenile hormone esterase, isoform B
(Trichoplusia ni) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis
Curated by ChEMBL
| Assay Description Inhibition of Trichoplusia ni (cabbage looper) juvenile hormone esterase isolated from fifth-intsar larval stage using [3H]JH 3 as substrate incubate... |
Chem Res Toxicol 14: 1563-72 (2001)
Article DOI: 10.1021/tx015508+ BindingDB Entry DOI: 10.7270/Q20004ZT |
More data for this Ligand-Target Pair | |
Carboxylesterase
(Sus scrofa) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis
Curated by ChEMBL
| Assay Description Inhibition of Sus scrofa (pig) carboxylesterase isolated from liver in using p-nitrophenyl acetate as substrate incubated for 5 min prior to substrat... |
Chem Res Toxicol 14: 1563-72 (2001)
Article DOI: 10.1021/tx015508+ BindingDB Entry DOI: 10.7270/Q20004ZT |
More data for this Ligand-Target Pair | |
Liver carboxylesterase B-1
(Rattus norvegicus) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California at Davis
Curated by ChEMBL
| Assay Description Inhibition of carboxylesterase in Fischer 344 Rattus norvegicus (rat) liver microsomes using p-nitrophenyl acetate as substrate incubated for 5 min p... |
Chem Res Toxicol 14: 1563-72 (2001)
Article DOI: 10.1021/tx015508+ BindingDB Entry DOI: 10.7270/Q20004ZT |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Calcium-independent phospholipase A2
(Homo sapiens (Human)) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS... |
J Med Chem 62: 1999-2007 (2019)
Article DOI: 10.1021/acs.jmedchem.8b01568 |
More data for this Ligand-Target Pair | |
Carboxylesterase
(Sus scrofa) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of pig liver carboxylesterase after 5 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |
Carboxylesterase
(Sus scrofa) | BDBM50371970
(CHEMBL89506)Show InChI InChI=1S/C11H19F3OS/c1-2-3-4-5-6-7-8-16-9-10(15)11(12,13)14/h2-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL DrugBank PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of pig liver carboxylesterase after 15 mins |
Bioorg Med Chem 16: 2114-30 (2008)
Article DOI: 10.1016/j.bmc.2007.10.081 BindingDB Entry DOI: 10.7270/Q2K938DT |
More data for this Ligand-Target Pair | |