| Reaction Details |
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 | Report a problem with these data |
| Target | 85/88 kDa calcium-independent phospholipase A2 |
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| Ligand | BDBM50371970 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1911004 (CHEMBL4413450) |
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| IC50 | 55±n/a nM |
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| Citation |  Mouchlis, VD; Armando, A; Dennis, EA Substrate-Specific Inhibition Constants for Phospholipase A J Med Chem62:1999-2007 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 85/88 kDa calcium-independent phospholipase A2 |
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| Name: | 85/88 kDa calcium-independent phospholipase A2 |
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| Synonyms: | Calcium-independent phospholipase A2 | PLA2G6 | PLPL9_HUMAN | PLPLA9 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 89913.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_156048 |
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| Residue: | 806 |
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| Sequence: | MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLV
NPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSW
SVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMD
VTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLL
LCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMA
RMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSK
DNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHG
VPAEQGSAAPHHPFSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMRDEKRTHDHL
LCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGM
YFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFR
NYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNP
TLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKT
VFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVN
ALWETEVYIYEHREEFQKLIQLLLSP
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| BDBM50371970 |
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| n/a |
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| Name | BDBM50371970 |
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| Synonyms: | CHEMBL89506 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H19F3OS |
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| Mol. Mass. | 256.328 |
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| SMILES | CCCCCCCCSCC(=O)C(F)(F)F |
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| Structure | 
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