BDBM50373837 CHEMBL429320

SMILES: CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl

InChI Key: InChIKey=XFHLEOOAWLOFHN-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50373837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50373837 (CHEMBL429320) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl Show InChI InChI=1S/C19H28ClN3O/c1-2-22-10-12-23(13-11-22)18-9-8-16(14-17(18)20)21-19(24)15-6-4-3-5-7-15/h8-9,14-15H,2-7,10-13H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M2 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50373837 (CHEMBL429320) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl Show InChI InChI=1S/C19H28ClN3O/c1-2-22-10-12-23(13-11-22)18-9-8-16(14-17(18)20)21-19(24)15-6-4-3-5-7-15/h8-9,14-15H,2-7,10-13H2,1H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M1 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (RAT)	BDBM50373837 (CHEMBL429320) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl Show InChI InChI=1S/C19H28ClN3O/c1-2-22-10-12-23(13-11-22)18-9-8-16(14-17(18)20)21-19(24)15-6-4-3-5-7-15/h8-9,14-15H,2-7,10-13H2,1H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (RAT)	BDBM50373837 (CHEMBL429320) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl Show InChI InChI=1S/C19H28ClN3O/c1-2-22-10-12-23(13-11-22)18-9-8-16(14-17(18)20)21-19(24)15-6-4-3-5-7-15/h8-9,14-15H,2-7,10-13H2,1H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M4 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50373837 (CHEMBL429320) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)C2CCCCC2)cc1Cl Show InChI InChI=1S/C19H28ClN3O/c1-2-22-10-12-23(13-11-22)18-9-8-16(14-17(18)20)21-19(24)15-6-4-3-5-7-15/h8-9,14-15H,2-7,10-13H2,1H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Institute of Chemical Biology Curated by ChEMBL					Assay Description Antagonist activity at rat muscarinic M3 receptor expressed in CHO cells by calcium mobilization assay				Bioorg Med Chem Lett 18: 885-90 (2008) Article DOI: 10.1016/j.bmcl.2007.12.051 BindingDB Entry DOI: 10.7270/Q2DZ095Z
					More data for this Ligand-Target Pair