BDBM50380067 CHEMBL2012765

SMILES: COCCn1cccc1C(OC)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F

InChI Key: InChIKey=GBXFIRKYLMIFBA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50380067 (CHEMBL2012765) Show SMILES COCCn1cccc1C(OC)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C23H25F3N2O4S/c1-27(33(29,30)20-8-5-4-6-9-20)19-13-11-18(12-14-19)22(32-3,23(24,25)26)21-10-7-15-28(21)16-17-31-2/h4-15H,16-17H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...				Bioorg Med Chem Lett 22: 2407-10 (2012) Article DOI: 10.1016/j.bmcl.2012.02.028 BindingDB Entry DOI: 10.7270/Q2M61M77
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50380067 (CHEMBL2012765) Show SMILES COCCn1cccc1C(OC)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C23H25F3N2O4S/c1-27(33(29,30)20-8-5-4-6-9-20)19-13-11-18(12-14-19)22(32-3,23(24,25)26)21-10-7-15-28(21)16-17-31-2/h4-15H,16-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...				Bioorg Med Chem Lett 22: 2407-10 (2012) Article DOI: 10.1016/j.bmcl.2012.02.028 BindingDB Entry DOI: 10.7270/Q2M61M77
					More data for this Ligand-Target Pair