BDBM50382410 CHEMBL2022568

SMILES: Cc1[nH]nc(C(O)=O)c1CCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=OUUYZJYPRXYIPJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxyacid oxidase 2 (Rattus norvegicus)	BDBM50382410 (CHEMBL2022568) Show SMILES Cc1[nH]nc(C(O)=O)c1CCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H18N2O2/c1-13-17(18(19(22)23)21-20-13)12-9-14-7-10-16(11-8-14)15-5-3-2-4-6-15/h2-8,10-11H,9,12H2,1H3,(H,20,21)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat His6-tagged Hao2 expressed in Escherichia coli BL21/DE3 using 2-hydroxyoctanoic acid as substrate measured every 10 secs by spectro...				ACS Med Chem Lett 2: 919-923 (2011) Article DOI: 10.1021/ml2001938 BindingDB Entry DOI: 10.7270/Q2JM2BN6
					More data for this Ligand-Target Pair
Hydroxyacid oxidase 2 (Rattus norvegicus)	BDBM50382410 (CHEMBL2022568) Show SMILES Cc1[nH]nc(C(O)=O)c1CCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H18N2O2/c1-13-17(18(19(22)23)21-20-13)12-9-14-7-10-16(11-8-14)15-5-3-2-4-6-15/h2-8,10-11H,9,12H2,1H3,(H,20,21)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Inhibition of rat Hao2-mediated oxidation of 2-hydroxyoctanoic acid assessed as proportionate release of H2O2				Bioorg Med Chem Lett 22: 4341-7 (2012) Article DOI: 10.1016/j.bmcl.2012.05.020 BindingDB Entry DOI: 10.7270/Q20866FZ
					More data for this Ligand-Target Pair