| Reaction Details |
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 | Report a problem with these data |
| Target | 2-Hydroxyacid oxidase 2 |
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| Ligand | BDBM50382410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_863190 (CHEMBL2175914) |
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| IC50 | 910±n/a nM |
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| Citation |  Barawkar, DA; Bandyopadhyay, A; Deshpande, A; Koul, S; Kandalkar, S; Patil, P; Khose, G; Vyas, S; Mone, M; Bhosale, S; Singh, U; De, S; Meru, A; Gundu, J; Chugh, A; Palle, VP; Mookhtiar, KA; Vacca, JP; Chakravarty, PK; Nargund, RP; Wright, SD; Roy, S; Graziano, MP; Cully, D; Cai, TQ; Singh, SB Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase. Bioorg Med Chem Lett22:4341-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-Hydroxyacid oxidase 2 |
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| Name: | 2-Hydroxyacid oxidase 2 |
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| Synonyms: | (S)-2-hydroxy-acid oxidase, peroxisomal | HAOX2_RAT | Hao2 | Hao3 | Haox2 | Hydroxyacid oxidase 2 | Long chain alpha-hydroxy acid oxidase | Long-chain L-2-hydroxy acid oxidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39204.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_863190 |
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| Residue: | 353 |
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| Sequence: | MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDT
RTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAA
PEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANIL
LKDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNV
QGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIF
LGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL
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| BDBM50382410 |
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| n/a |
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| Name | BDBM50382410 |
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| Synonyms: | CHEMBL2022568 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O2 |
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| Mol. Mass. | 306.3584 |
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| SMILES | Cc1[nH]nc(C(O)=O)c1CCc1ccc(cc1)-c1ccccc1 |
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| Structure | 
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