BDBM50385446 CHEMBL2036747

SMILES: O=C(Nc1ccc(cc1)N1CCOCC1)c1nnc(NC(=O)c2ccccc2)o1

InChI Key: InChIKey=SIQZBMCHNIQQOL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50385446 (CHEMBL2036747) Show SMILES O=C(Nc1ccc(cc1)N1CCOCC1)c1nnc(NC(=O)c2ccccc2)o1 Show InChI InChI=1S/C20H19N5O4/c26-17(14-4-2-1-3-5-14)22-20-24-23-19(29-20)18(27)21-15-6-8-16(9-7-15)25-10-12-28-13-11-25/h1-9H,10-13H2,(H,21,27)(H,22,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...				Bioorg Med Chem Lett 22: 3873-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.117 BindingDB Entry DOI: 10.7270/Q2T72JG4
					More data for this Ligand-Target Pair