BDBM50399702 CHEMBL2178389

SMILES: CCc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1

InChI Key: InChIKey=AQOIGZWADDGQMU-SHTZXODSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM50399702 (CHEMBL2178389) Show SMILES CCc1nc(C)c(nc1C(N)=O)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 |r,wU:18.19,wD:21.23,(61.37,-52.27,;62.71,-53.04,;64.04,-52.27,;65.38,-53.04,;66.71,-52.27,;68.05,-53.04,;66.71,-50.74,;65.38,-49.96,;64.04,-50.73,;62.71,-49.96,;61.38,-50.73,;62.71,-48.42,;68.04,-49.97,;69.38,-50.74,;70.71,-49.97,;70.71,-48.42,;69.37,-47.65,;68.04,-48.42,;72.04,-47.65,;72.03,-46.11,;73.37,-45.34,;74.71,-46.11,;76.04,-45.34,;77.37,-46.11,;78.71,-45.34,;77.37,-47.65,;74.7,-47.65,;73.38,-48.42,)| Show InChI InChI=1S/C22H27N3O3/c1-3-18-21(22(23)28)25-20(13(2)24-18)17-10-8-16(9-11-17)15-6-4-14(5-7-15)12-19(26)27/h8-11,14-15H,3-7,12H2,1-2H3,(H2,23,28)(H,26,27)/t14-,15-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
					More data for this Ligand-Target Pair