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SMILES: Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1

InChI Key: InChIKey=PSGBSWDRJJWEDY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50408151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B/3C/3D/3E (Homo sapiens (Human))	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Sus scrofa)	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (BOVINE)	BDBM50408151 (CHEMBL299524) Show SMILES Fc1ccc(CN2CCN(Cc3nc4ccccc4n4cccc34)CC2)cc1 Show InChI InChI=1S/C23H23FN4/c24-19-9-7-18(8-10-19)16-26-12-14-27(15-13-26)17-21-23-6-3-11-28(23)22-5-2-1-4-20(22)25-21/h1-11H,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligand				J Med Chem 40: 1808-19 (1997) Article DOI: 10.1021/jm960501o BindingDB Entry DOI: 10.7270/Q20R9QMC
					More data for this Ligand-Target Pair