BDBM50413143 CHEMBL471214

SMILES: CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NC2CCN(CC3CC3)C2)cc1

InChI Key: InChIKey=DPTWSDMDTMQUMF-GITCGBDTSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50413143 (CHEMBL471214) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NC2CCN(CC3CC3)C2)cc1 |r| Show InChI InChI=1S/C27H34N4O5/c1-2-36-26(34)20-7-9-21(10-8-20)29-27(35)30-24(15-18-5-11-23(32)12-6-18)25(33)28-22-13-14-31(17-22)16-19-3-4-19/h5-12,19,22,24,32H,2-4,13-17H2,1H3,(H,28,33)(H2,29,30,35)/t22?,24-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50413143 (CHEMBL471214) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NC2CCN(CC3CC3)C2)cc1 |r| Show InChI InChI=1S/C27H34N4O5/c1-2-36-26(34)20-7-9-21(10-8-20)29-27(35)30-24(15-18-5-11-23(32)12-6-18)25(33)28-22-13-14-31(17-22)16-19-3-4-19/h5-12,19,22,24,32H,2-4,13-17H2,1H3,(H,28,33)(H2,29,30,35)/t22?,24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced intracellular ...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50413143 (CHEMBL471214) Show SMILES CCOC(=O)c1ccc(NC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)NC2CCN(CC3CC3)C2)cc1 |r| Show InChI InChI=1S/C27H34N4O5/c1-2-36-26(34)20-7-9-21(10-8-20)29-27(35)30-24(15-18-5-11-23(32)12-6-18)25(33)28-22-13-14-31(17-22)16-19-3-4-19/h5-12,19,22,24,32H,2-4,13-17H2,1H3,(H,28,33)(H2,29,30,35)/t22?,24-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant muscarinic M2 receptor expressed in CHO cells coexpressing chimeric G protein Gqi5 assessed as inhibition of...				Bioorg Med Chem Lett 18: 5481-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.020 BindingDB Entry DOI: 10.7270/Q23B61CM
					More data for this Ligand-Target Pair