BDBM50416356 CHEMBL1172180

SMILES: CC(C)N1C(=O)c2ccccc2CC1(CCN(C)C)c1ccc(Cl)cc1

InChI Key: InChIKey=HHAVLXMLYHADSP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin-2 (Homo sapiens (Human))	BDBM50416356 (CHEMBL1172180) Show SMILES CC(C)N1C(=O)c2ccccc2CC1(CCN(C)C)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H27ClN2O/c1-16(2)25-21(26)20-8-6-5-7-17(20)15-22(25,13-14-24(3)4)18-9-11-19(23)12-10-18/h5-12,16H,13-15H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a
University of Gothenburg Curated by ChEMBL					Assay Description Agonist activity against human urotensin 2 receptor expressed in human NIH373 cells assessed as beta-galactosidase activity after 5 days by R-SAT ass...				Bioorg Med Chem 18: 4844-54 (2011) Article DOI: 10.1016/j.bmc.2010.04.041 BindingDB Entry DOI: 10.7270/Q2PG1SZ3
					More data for this Ligand-Target Pair