BDBM50417428 CHEMBL1290184

SMILES: Cc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccccc2)c1

InChI Key: InChIKey=BOXHESMXGWQKOM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50417428 (CHEMBL1290184) Show SMILES Cc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H30N2O/c1-20-6-5-7-21(18-20)19-25-14-10-24(11-15-25)12-16-26(17-13-24)23(27)22-8-3-2-4-9-22/h2-9,18H,10-17,19H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50417428 (CHEMBL1290184) Show SMILES Cc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C24H30N2O/c1-20-6-5-7-21(18-20)19-25-14-10-24(11-15-25)12-16-26(17-13-24)23(27)22-8-3-2-4-9-22/h2-9,18H,10-17,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 7458-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.016 BindingDB Entry DOI: 10.7270/Q2GM88K4
					More data for this Ligand-Target Pair