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BDBM50421510 CHEMBL239127

SMILES: [#6]-[#6]-[#6@H](-[#6])-[#6@@H]-1-[#7]-[#6](=O)-[#6@@H]-2-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6@@H]-2-[#6]-[#6]-[#6]-[#7]-2-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H]-2-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6]-1=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-2)-[#6@@H](-[#6])-[#8])-[#6@@H](-[#6])-[#6]-[#6]

InChI Key: InChIKey=QQBRBPSSMDPLLA-ROPOSLPCSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50421510
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Trypsin (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of Sunflower beta-trypsin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Matriptase (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of Matriptase from human breast cancer cells				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of bovine beta trypsin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Thrombin (Bos taurus (Bovine))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for inhibition of bovine Thrombin				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase receptor (uPAR) (Homo sapiens (Human))	BDBM50421510 (CHEMBL239127) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Compound was tested for microPa) Urokinase-type plasminogen activator from human urine				Bioorg Med Chem Lett 11: 2515-9 (2001) BindingDB Entry DOI: 10.7270/Q2TH8M0Q
National Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair