BDBM50425869 CHEMBL2312653
SMILES: Cc1cc(on1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1NC1CCNCC1
InChI Key: InChIKey=SFMKVXGJJGANQK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50425869 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50425869
(CHEMBL2312653)Show SMILES Cc1cc(on1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1NC1CCNCC1 Show InChI InChI=1S/C19H20Cl2N6O/c1-11-6-17(28-27-11)16-10-23-19(25-15-8-12(20)7-13(21)9-15)26-18(16)24-14-2-4-22-5-3-14/h6-10,14,22H,2-5H2,1H3,(H2,23,24,25,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATP |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
P-selectin/P-selectin glycoprotein ligand 1
(Homo sapiens (Human)) | BDBM50425869
(CHEMBL2312653)Show SMILES Cc1cc(on1)-c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1NC1CCNCC1 Show InChI InChI=1S/C19H20Cl2N6O/c1-11-6-17(28-27-11)16-10-23-19(25-15-8-12(20)7-13(21)9-15)26-18(16)24-14-2-4-22-5-3-14/h6-10,14,22H,2-5H2,1H3,(H2,23,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of P-selectin aggregation in platelet surface (unknown origin) |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
Search and Browse
