BDBM50431272 CHEMBL2333032::US9428465, 3

SMILES: CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O

InChI Key: InChIKey=MVWIGWIKOQYGRO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50431272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (AC) (Rattus norvegicus (Rat))	BDBM50431272 (CHEMBL2333032 | US9428465, 3) Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (AC) (Rattus norvegicus (Rat))	BDBM50431272 (CHEMBL2333032 | US9428465, 3) Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair