BDBM50431279 CHEMBL2346680

SMILES: Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O

InChI Key: InChIKey=DNINGYYWXPRQDJ-UHFFFAOYSA-N

Data: 6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to TYRO3 (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to MET (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to nonphosphorylated ABL1 (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to AXL (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to phosphorylated ABL1 (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50431279 (CHEMBL2346680) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4nc[nH]c34)c(F)c2)c1=O Show InChI InChI=1S/C23H14F2N6O3/c24-13-3-6-15(7-4-13)31-9-1-2-16(23(31)33)21(32)30-14-5-8-18(17(25)10-14)34-22-19-20(27-11-26-19)28-12-29-22/h1-12H,(H,30,32)(H,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Binding affinity to MER (unknown origin) after 1 hr				Eur J Med Chem 61: 2-25 (2013) Article DOI: 10.1016/j.ejmech.2012.06.005 BindingDB Entry DOI: 10.7270/Q2V40WJP
					More data for this Ligand-Target Pair