BDBM50432157 CHEMBL2346778

SMILES: OC(=O)c1cccc(NC(=O)NCCC(c2ccccc2)c2ccccc2)c1

InChI Key: InChIKey=KMBNSFUPPWYBSK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50432157 (CHEMBL2346778) Show SMILES OC(=O)c1cccc(NC(=O)NCCC(c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C23H22N2O3/c26-22(27)19-12-7-13-20(16-19)25-23(28)24-15-14-21(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-13,16,21H,14-15H2,(H,26,27)(H2,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Galapagos SASU Curated by ChEMBL					Assay Description Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 2451-4 (2013) Article DOI: 10.1016/j.bmcl.2013.01.078 BindingDB Entry DOI: 10.7270/Q2930VJZ
					More data for this Ligand-Target Pair