BDBM50434483 CHEMBL2385164

SMILES: CNc1ccc(C=Cc2nc3ccc(I)cc3[nH]2)cc1

InChI Key: InChIKey=UACJAEPUZXTOBN-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50434483 (CHEMBL2385164) Show SMILES CNc1ccc(C=Cc2nc3ccc(I)cc3[nH]2)cc1 |w:7.7| Show InChI InChI=1S/C16H14IN3/c1-18-13-6-2-11(3-7-13)4-9-16-19-14-8-5-12(17)10-15(14)20-16/h2-10,18H,1H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Binding affinity to recombinant human tau (441 amino acid residues) aggregates expressed in Escherichia coli assessed as apparent dissociation consta...				Bioorg Med Chem 21: 3356-62 (2013) Article DOI: 10.1016/j.bmc.2013.02.054 BindingDB Entry DOI: 10.7270/Q23J3FB2
					More data for this Ligand-Target Pair