BDBM50444066 CHEMBL3092799

SMILES: CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1

InChI Key: InChIKey=JNYMZWUOQWXOII-SHTZXODSSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444066 (CHEMBL3092799) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)| Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444066 (CHEMBL3092799) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)| Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444066 (CHEMBL3092799) Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](N)CC2)n1)-c1ccccn1 |r,wU:11.10,wD:14.14,(15.98,-7.45,;17.32,-6.68,;18.65,-7.45,;19.98,-6.68,;21.32,-7.45,;22.65,-6.69,;23.98,-7.46,;25.32,-6.68,;25.32,-5.13,;23.98,-4.37,;23.98,-2.83,;22.64,-2.06,;21.31,-2.84,;19.98,-2.06,;19.98,-.52,;18.64,.26,;21.31,.25,;22.64,-.52,;22.65,-5.14,;26.65,-4.36,;27.98,-5.13,;29.31,-4.36,;29.3,-2.81,;27.96,-2.05,;26.64,-2.82,)| Show InChI InChI=1S/C19H28N6/c1-2-3-11-22-19-23-13-16(17-6-4-5-12-21-17)18(25-19)24-15-9-7-14(20)8-10-15/h4-6,12-15H,2-3,7-11,20H2,1H3,(H2,22,23,24,25)/t14-,15-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9683-92 (2014) Article DOI: 10.1021/jm401387j BindingDB Entry DOI: 10.7270/Q29W0GX8
					More data for this Ligand-Target Pair